Patchouli alcohol protects against chronic unpredictable mild stress-induced depressant-like behavior through inhibiting excessive autophagy via activation of mTOR signaling pathway
Patchouli alcohol (PA), a tricyclic sesquiterpene, is the major chemical component of patchouli oil. This study investigated the antidepressant-like effect and mechanism of PA in chronic unpredictable mild stress (CUMS). Our results showed that PA markedly attenuated CUMS-induced depressant-like beh...
Main Authors: | Jianyi Zhuo, Baoyi Chen, Chaoyue Sun, Tao Jiang, Zhiwei Chen, Yanlu Liu, Juan Nie, Hongmei Yang, Jingna Zheng, Xiaoping Lai, Ziren Su, Chuwen Li, Yucui Li |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-07-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332220303073 |
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