N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

Abstract Background Transcriptome analytic tools are commonly used across patient cohorts to develop drugs and predict clinical outcomes. However, as precision medicine pursues more accurate and individualized treatment decisions, these methods are not designed to address single-patient transcriptom...

Full description

Bibliographic Details
Main Authors: Qike Li, A. Grant Schissler, Vincent Gardeux, Ikbel Achour, Colleen Kenost, Joanne Berghout, Haiquan Li, Hao Helen Zhang, Yves A. Lussier
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Medical Genomics
Subjects:
Precision Medicine
Single-Subject Analysis
N-of-1-pathways
Mixture Model
RNA-Seq
Head and neck squamous cell carcinomas (HNSCCs)
Online Access:http://link.springer.com/article/10.1186/s12920-017-0263-4

Internet

http://link.springer.com/article/10.1186/s12920-017-0263-4

Similar Items