Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF-κB Pathway

In this study, we demonstrated that temozolomide (TMZ) and propyl gallate (PG) combination enhanced the inhibition of migration in human U87MG glioma cells. PG inhibited the TMZ-induced reactive oxygen species (ROS) generation. The mitochondrial complex III and NADPH oxidase are two critical sites t...

Full description

Bibliographic Details
Main Authors: Jen-Tsung Yang, I-Neng Lee, Fung-Jou Lu, Chiu-Yen Chung, Ming-Hsueh Lee, Yu-Ching Cheng, Kuo-Tai Chen, Ching-Hsein Chen
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2017/9489383