The effects of magnesium sulfate infiltration on perioperative opioid consumption and opioid-induced hyperalgesia in patients undergoing robot-assisted laparoscopic prostatectomy with remifentanil-based anesthesia

The effects of magnesium sulfate infiltration on perioperative opioid consumption and opioid-induced hyperalgesia in patients undergoing robot-assisted laparoscopic prostatectomy with remifentanil-based anesthesia

BackgroundOpioids not only exert an antinociceptive effect, but also modulate central N-methyl-D-aspartate (NMDA) receptors, resulting in hyperalgesia and acute opioid tolerance. This study was aimed to investigate the effect of the NMDA receptor antagonist, magnesium in preventing remifentanil-indu...

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Bibliographic Details
Main Authors: Cheol Lee, Yoon-Kang Song, Hyun-Myun Jeong, Seong-Nam Park
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2011-09-01
Series:Korean Journal of Anesthesiology
Subjects:
magnesium sulfate
nmda receptor
opioid induced hyperalgesia
remifentanil
Online Access:http://ekja.org/upload/pdf/kjae-61-244.pdf

Internet

http://ekja.org/upload/pdf/kjae-61-244.pdf

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