WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function.

WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function.

In a recent genome-wide association study, WD-repeat domain 12 (WDR12) was associated with early-onset myocardial infarction (MI). However, the function of WDR12 in the heart is unknown.We characterized cardiac expression of WDR12, used adenovirus-mediated WDR12 gene delivery to examine effects of W...

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Bibliographic Details
Main Authors: Anne-Mari Moilanen, Jaana Rysä, Leena Kaikkonen, Teemu Karvonen, Erja Mustonen, Raisa Serpi, Zoltán Szabó, Olli Tenhunen, Zsolt Bagyura, Juha Näpänkangas, Pauli Ohukainen, Pasi Tavi, Risto Kerkelä, Margrét Leósdóttir, Björn Wahlstrand, Thomas Hedner, Olle Melander, Heikki Ruskoaho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4411154?pdf=render

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http://europepmc.org/articles/PMC4411154?pdf=render

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