Prevention and management of diarrhea associated with naldemedine among patients receiving opioids: a retrospective cohort study
Abstract Background Naldemedine, a novel peripherally-acting mu-opioid receptor antagonist, has improved opioid-induced constipation in randomized controlled trials. The most frequent adverse event of naldemedine is diarrhea, which can cause abdominal pain and often leads to treatment discontinuatio...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | BMC Gastroenterology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12876-020-1173-z |