RUNX3 Inhibits the Invasion and Metastasis of Human Colon Cancer HT-29 Cells by Upregulating MMP-2/9

Objective. To investigate the effect of Runt-associated transcription factor 3 (RUNX3) on the invasion and metastasis of human colon cancer HT-29 cells and to preliminarily explore the mechanism of its anticancer effect. Methods. The RUNX3 plasmid vector was transfected into human colon cancer HT-29...

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Bibliographic Details
Main Authors: Jun Xue, Xueliang Wu, Ming Qu, Fei Guo, Lei Han, Guangyuan Sun, Zelong Yuan, Shuang Fan, Tian Li
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2020/5978131