Estimation of Diabetes Risk in Brazilian Population by Typing for Polymorphisms in HLA-DR-DQ, INS and CTLA-4 Genes

The study aimed to further characterise HLA encoded risk factors of type 1 diabetes (T1D) in Brazilian population and test the capability of a low resolution full-house DR-DQ typing method to find subjects at diabetes risk. Insulin and CTLA-4 gene polymorphisms were also analysed. The method is base...

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Bibliographic Details
Main Authors: Omar M. Hauache, André F. Reis, Carolina S.V. Oliveira, José Gilberto H. Vieira, Minna Sjüroos, Jorma Ilonen
Format: Article
Language:English
Published: Hindawi Limited 2005-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2005/684123