Next generation of immune checkpoint inhibitors and beyond

Abstract The immune system is the core defense against cancer development and progression. Failure of the immune system to recognize and eliminate malignant cells plays an important role in the pathogenesis of cancer. Tumor cells evade immune recognition, in part, due to the immunosuppressive featur...

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Bibliographic Details
Main Authors: Julian A. Marin-Acevedo, ErinMarie O. Kimbrough, Yanyan Lou
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-021-01056-8