Magnolol Suppresses Pancreatic Cancer Development In Vivo and In Vitro via Negatively Regulating TGF-β/Smad Signaling

Magnolol Suppresses Pancreatic Cancer Development In Vivo and In Vitro via Negatively Regulating TGF-β/Smad Signaling

Magnolol, a hydroxylated biphenyl extracted from Magnolia officinalis, has recently drawn attention due to its anticancer potential. The present study was aimed to explore the effects of Magnolol on restraining the proliferation, migration and invasion of pancreatic cancer in vivo and in vitro. Magn...

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Bibliographic Details
Main Authors: Shuo Chen, Jiaqi Shen, Jing Zhao, Jiazhong Wang, Tao Shan, Junhui Li, Meng Xu, Xi Chen, Yang Liu, Gang Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
magnolol
pancreatic cancer
TGF-β
epithelial-mesenchymal-transition
Smad
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.597672/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.597672/full

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