Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression

Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression

Osteosarcoma is a highly aggressive malignant tumor, which most commonly occurs in children and adolescents. This study aims to reveal that hypoxia promotes the invasion of osteosarcoma cells by up-regulating the expression of NUSAP1. The expression of HIF-1α and NUSAP1 was significantly up-regulate...

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Bibliographic Details
Main Authors: Zhang Ling, Song Jingtao, Xin Xu, Sun Donghong, Huang Huiting, Chen Yang, Zhang Tao, Zhang Yiming
Format: Article
Language:English
Published: De Gruyter 2021-07-01
Series:Open Medicine
Subjects:
osteosarcoma
hypoxia
hif-1α
nusap1
migration
invasion
Online Access:https://doi.org/10.1515/med-2020-0180

Internet

https://doi.org/10.1515/med-2020-0180

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