Random X inactivation and extensive mosaicism in human placenta revealed by analysis of allele-specific gene expression along the X chromosome.

Random X inactivation and extensive mosaicism in human placenta revealed by analysis of allele-specific gene expression along the X chromosome.

Imprinted inactivation of the paternal X chromosome in marsupials is the primordial mechanism of dosage compensation for X-linked genes between females and males in Therians. In Eutherian mammals, X chromosome inactivation (XCI) evolved into a random process in cells from the embryo proper, where ei...

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Bibliographic Details
Main Authors: Joana Carvalho Moreira de Mello, Erica Sara Souza de Araújo, Raquel Stabellini, Ana Maria Fraga, Jorge Estefano Santana de Souza, Denilce R Sumita, Anamaria A Camargo, Lygia V Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2881032?pdf=render

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http://europepmc.org/articles/PMC2881032?pdf=render

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