Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains.

Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains.

SMXA-5 mice are a high-fat diet-induced type 2 diabetes animal model established from non-diabetic SM/J and A/J mice. By using F2 intercross mice between SMXA-5 and SM/J mice under feeding with a high-fat diet, we previously mapped a major diabetogenic QTL (T2dm2sa) on chromosome 2. We then produced...

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Bibliographic Details
Main Authors: Misato Kobayashi, Tamio Ohno, Kunio Ihara, Atsushi Murai, Mayumi Kumazawa, Hiromi Hoshino, Koichiro Iwanaga, Hiroshi Iwai, Yoshiki Hamana, Mikako Ito, Kinji Ohno, Fumihiko Horio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4006839?pdf=render

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http://europepmc.org/articles/PMC4006839?pdf=render

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