Design, Synthesis and In Vitro Characterization of Novel Antimicrobial Agents Based on 6-Chloro-9<i>H</i>-carbazol Derivatives and 1,3,4-Oxadiazole Scaffolds

In this paper, we aimed to exploit and combine in the same molecule the carbazole and the 1,3,4-oxadiazole pharmacophores, to obtain novel carprofen derivatives, by using two synthesis pathways. For the first route, the following steps have been followed: (i) (<i>RS</i>)-2-(6-chloro-9<...

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Bibliographic Details
Main Authors: Alexandra T. Bordei Telehoiu, Diana C. Nuță, Miron T. Căproiu, Florea Dumitrascu, Irina Zarafu, Petre Ioniță, Carmellina D. Bădiceanu, Speranța Avram, Mariana C. Chifiriuc, Coralia Bleotu, Carmen Limban
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/2/266