Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell‐Based Treatments

Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell‐Based Treatments

Abstract Subretinal delivery of stem cell‐derived retinal cells as a strategy to treat retinal degenerative blindness holds great promise. Currently, two clinical trials are underway in which human fetal retinal progenitor cells (RPCs) are being delivered to patients by intravitreal or subretinal in...

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Bibliographic Details
Main Authors: Brittni A. Scruggs, Chunhua Jiao, Cathryn M. Cranston, Emily Kaalberg, Kai Wang, Stephen R. Russell, Luke A. Wiley, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker, Elliott H. Sohn
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Stem Cells Translational Medicine
Subjects:
Induced pluripotent stem cells
Retinal progenitor cells
Stem cell transplantation
Subretinal transplantation
Inherited retinal dystrophy
Pig model
Online Access:https://doi.org/10.1002/sctm.18-0210

Internet

https://doi.org/10.1002/sctm.18-0210

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