Strand breaks and chemical modification of intracellular DNA induced by cold atmospheric pressure plasma irradiation.

DNA damage in the A549 human lung cancer cell line treated with cold plasma irradiation was investigated. We confirmed that cold atmospheric plasma generated reactive oxygen and nitrogen species (RONS) in a liquid, and the intracellular RONS level was increased in plasma-irradiated cells. However, a...

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Bibliographic Details
Main Authors: Hirofumi Kurita, Natsuki Haruta, Yoshito Uchihashi, Takahito Seto, Kazunori Takashima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232724