Genetic variation of the IL-28B promoter affecting gene expression.

The current standard of care for the treatment of chronic hepatitis C is pegylated interferon-α (PEG-IFNα) and ribavirin (RBV). The treatment achieves a sustained viral clearance in only approximately 50% of patients. Recent whole genome association studies revealed that single nucleotide polymorphi...

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Bibliographic Details
Main Authors: Masaya Sugiyama, Yasuhito Tanaka, Takaji Wakita, Makoto Nakanishi, Masashi Mizokami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22046316/?tool=EBI