Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8+ T cells.

Clinical evaluation of immune reconstitution and health status during HIV-1 infection and anti-retroviral therapy (ART) is largely based on CD4+ T cell counts and viral load, measures that fail to take into account the CD8+ T cell subset, known to show features of accelerated aging in HIV disease. H...

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Bibliographic Details
Main Authors: Jennifer P Chou, Christina M Ramirez, Jennifer E Wu, Rita B Effros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3661524?pdf=render