JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk

JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk

Abstract Background Important insight into the mechanisms through which gene-environmental interactions cause schizophrenia can be achieved through preclinical studies combining prenatal immune stimuli with disease-related genetic risk modifications. Accumulating evidence associates JNK signalling m...

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Bibliographic Details
Main Authors: Rebecca L. Openshaw, Jaedeok Kwon, Alison McColl, Josef M. Penninger, Jonathan Cavanagh, Judith A. Pratt, Brian J. Morris
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Neuroinflammation
Subjects:
Neurodevelopment
Chemokine
ip-10
RANTES
sdf-1
TLR3
Online Access:http://link.springer.com/article/10.1186/s12974-019-1408-5

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http://link.springer.com/article/10.1186/s12974-019-1408-5

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