Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway

Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway

Abstract Background The increase in the levels of reactive oxygen species (ROS) in acute myeloid leukemia (AML) patients has been previously described; thus, it is important to regulate ROS levels in AML. Methods Flow cytometry were used to assess the in vitro effect of compound kushen injection (CK...

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Bibliographic Details
Main Authors: Yanxia Jin, Qian Yang, Li Liang, Lu Ding, Yuxing Liang, Dongdong Zhang, Balu Wu, Tian Yang, Hailing Liu, Tingting Huang, Hui Shen, Honglei Tu, Yunbao Pan, Yongchang Wei, Yi Yang, Fuling Zhou
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Acute myeloid leukaemia
Reactive oxygen species
Compound kushen injection
Peroxiredoxin-3
Peroxiredoxin-2
Online Access:http://link.springer.com/article/10.1186/s13046-018-0948-3

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http://link.springer.com/article/10.1186/s13046-018-0948-3

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