Biventricular adaptation to volume overload in mice with aortic regurgitation

<p>Abstract</p> <p>Background</p> <p>Aortic valve regurgitation is usually caused by impaired coaptation of the aortic valve cusps during diastole. Hypercholesterolemia produces aortic valve lipid deposition, fibrosis, and calcification in both mice and humans, which co...

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Bibliographic Details
Main Authors: Young Stephen G, Thedens Daniel R, McGroary KellyAnn, Miller Jordan D, Berry Christopher J, Heistad Donald D, Weiss Robert M
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Journal of Cardiovascular Magnetic Resonance
Online Access:http://www.jcmr-online.com/content/11/1/27