Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort

Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort

Abstract Background Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by osteoprotegerin (OPG). We have previously shown that circulating soluble...

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Main Authors: Danja Sarink, Helena Schock, Theron Johnson, Jenny Chang-Claude, Kim Overvad, Anja Olsen, Anne Tjønneland, Patrick Arveux, Agnès Fournier, Marina Kvaskoff, Heiner Boeing, Anna Karakatsani, Antonia Trichopoulou, Carlo La Vecchia, Giovanna Masala, Claudia Agnoli, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Carla H. van Gils, Petra H. M. Peeters, Elisabete Weiderpass, Antonio Agudo, Miguel Rodríguez-Barranco, José María Huerta, Eva Ardanaz, Leire Gil, Kay Tee Kaw, Julie A. Schmidt, Laure Dossus, Mathilde His, Dagfinn Aune, Elio Riboli, Rudolf Kaaks, Renée T. Fortner
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Breast cancer
Reproductive, hormonal, and related factors
Epidemiology
Serum biomarkers of endogenous exposures
Online Access:http://link.springer.com/article/10.1186/s12885-018-4887-3

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http://link.springer.com/article/10.1186/s12885-018-4887-3

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