A novel fiber-2-edited live attenuated vaccine candidate against the highly pathogenic serotype 4 fowl adenovirus

A novel fiber-2-edited live attenuated vaccine candidate against the highly pathogenic serotype 4 fowl adenovirus

Abstract Recently, the outbreaks of hydropericardium-hepatitis syndrome (HHS) caused by the highly pathogenic fowl adenovirus serotype 4 (FAdV-4) have resulted in huge economic losses to the poultry industry globally. Although several inactivated or subunit vaccines have been developed against FAdV-...

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Bibliographic Details
Main Authors: Quan Xie, Shiya Cao, Wei Zhang, Weikang Wang, Luyuan Li, Qiuqi Kan, Hui Fu, Tuoyu Geng, Tuofan Li, Zhimin Wan, Wei Gao, Hongxia Shao, Aijian Qin, Jianqiang Ye
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Veterinary Research
Subjects:
FAdV-4
CRISPR/Cas9
Recombinant virus
Attenuation
Vaccine candidate
Online Access:https://doi.org/10.1186/s13567-021-00907-z

Internet

https://doi.org/10.1186/s13567-021-00907-z

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