miRNA let-7e modulates the Wnt pathway and early nephrogenic markers in mouse embryonic stem cell differentiation.

miRNA let-7e modulates the Wnt pathway and early nephrogenic markers in mouse embryonic stem cell differentiation.

This study indicates that embryonic stem cells [ESCs] cultured with retinoic acid and activin A significantly upregulate the miRNA let-7e. This specific miRNA modulates the Wnt pathway and the expression of early nephrogenic markers under these differentiation conditions. The differentiation markers...

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Bibliographic Details
Main Authors: Jose Luis Viñas, Marina Ventayol, Bernhard Brüne, Michaela Jung, Anna Sola, Felip Pi, Chrysoula Mastora, Georgina Hotter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3622609?pdf=render

Internet

http://europepmc.org/articles/PMC3622609?pdf=render

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