An in vitro model of latency and reactivation of varicella zoster virus in human stem cell-derived neurons.

Varicella zoster virus (VZV) latency in sensory and autonomic neurons has remained enigmatic and difficult to study, and experimental reactivation has not yet been achieved. We have previously shown that human embryonic stem cell (hESC)-derived neurons are permissive to a productive and spreading VZ...

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Bibliographic Details
Main Authors: Amos Markus, Ilana Lebenthal-Loinger, In Hong Yang, Paul R Kinchington, Ronald S Goldstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4456082?pdf=render