Cooperation Between Cancer and Fibroblasts in Vascular Mimicry and N2-Type Neutrophil Recruitment via Notch2–Jagged1 Interaction in Lung Cancer

Cooperation Between Cancer and Fibroblasts in Vascular Mimicry and N2-Type Neutrophil Recruitment via Notch2–Jagged1 Interaction in Lung Cancer

BackgroundAngiogenesis is required for tumor development and metastasis, which is a major part in a pro-tumor microenvironment. Vascular mimicry (VM) is a process in which cancer cells, rather than endothelia, create an alternative perfusion system to support the tumor progression.ObjectivesTo valid...

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Bibliographic Details
Main Authors: Ying-Ming Tsai, Kuan-Li Wu, Yu-Wei Liu, Wei-An Chang, Yung-Chi Huang, Chao-Yuan Chang, Pei-Hsun Tsai, Szi-Hui Liao, Jen-Yu Hung, Ya-Ling Hsu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
cancer-associated fibroblasts
Jagged1
lung cancer
Notch2
vascular mimicry
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.696931/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.696931/full

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