Thymidine Analogues for Tracking DNA Synthesis

Replicating cells undergo DNA synthesis in the highly regulated, S-phase of the cell cycle. Analogues of the pyrimidine deoxynucleoside thymidine may be inserted into replicating DNA, effectively tagging dividing cells allowing their characterisation. Tritiated thymidine, targeted using autoradiogra...

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Bibliographic Details
Main Authors: Brenton L. Cavanagh, Anwar Norazit, Tom Walker, Adrian C.B. Meedeniya
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/9/7980/