Different rates of spontaneous mutation of chloroplastic and nuclear viroids as determined by high-fidelity ultra-deep sequencing.

Mutation rates vary by orders of magnitude across biological systems, being higher for simpler genomes. The simplest known genomes correspond to viroids, subviral plant replicons constituted by circular non-coding RNAs of few hundred bases. Previous work has revealed an extremely high mutation rate...

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Bibliographic Details
Main Authors: Amparo López-Carrasco, Cristina Ballesteros, Vicente Sentandreu, Sonia Delgado, Selma Gago-Zachert, Ricardo Flores, Rafael Sanjuán
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006547