OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages

OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages

Background: Hyperamyloidosis in the brain is known as the earliest neuropathological change and a unique etiological factor in Alzheimer's disease (AD), while progressive neurodegeneration in certain vulnerable brain regions forms the basis of clinical syndromes. It is not clear how early hyper...

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Bibliographic Details
Main Authors: Xuping Li, Lin Wang, Matthew Cykowski, Tiancheng He, Timothy Liu, Joshua Chakranarayan, Andreana Rivera, Hong Zhao, Suzanne Powell, Weiming Xia, Stephen T.C. Wong
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419307790

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http://www.sciencedirect.com/science/article/pii/S2352396419307790

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