Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice

Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice

Abstract Background 211At is one of the ideal nuclides for targeted radionuclide therapies (TRTs). Meta-[211At]astatobenzylguanidine (211At-MABG) has been proposed for the treatment of pheochromocytoma. To effectively use these radiopharmaceuticals, dosimetry must be performed. It is important to de...

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Bibliographic Details
Main Authors: Naoyuki Ukon, Songji Zhao, Kohshin Washiyama, Noboru Oriuchi, Chengbo Tan, Saki Shimoyama, Miho Aoki, Hitoshi Kubo, Kazuhiro Takahashi, Hiroshi Ito
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:EJNMMI Physics
Subjects:
Alpha-emitter
Meta-[211At]astatobenzylguanidine
Dosimetry
Radionuclide therapy
Online Access:http://link.springer.com/article/10.1186/s40658-020-00326-7

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http://link.springer.com/article/10.1186/s40658-020-00326-7

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