IL-33 Is Essential for Adjuvant Effect of Hydroxypropyl-β-Cyclodexrin on the Protective Intranasal Influenza Vaccination

IL-33 Is Essential for Adjuvant Effect of Hydroxypropyl-β-Cyclodexrin on the Protective Intranasal Influenza Vaccination

Vaccine adjuvants are traditionally used to augment and modulate the immunogenicity of vaccines, although in many cases it is unclear which specific molecules contribute to their stimulatory activity. We previously reported that both subcutaneous and intranasal administration of hydroxypropyl-β-cycl...

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Bibliographic Details
Main Authors: Shingo Kobari, Takato Kusakabe, Masatoshi Momota, Takayuki Shibahara, Tomoya Hayashi, Koji Ozasa, Hideaki Morita, Kenji Matsumoto, Hirohisa Saito, Shuichi Ito, Etsushi Kuroda, Ken J. Ishii
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
IL-1α
IL-13
lung
DAMPs
ST2
AT2
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00360/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00360/full

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