Combined subthalamic and nucleus basalis of Meynert deep brain stimulation for Parkinson’s disease with dementia (DEMPARK-DBS): protocol of a randomized, sham-controlled trial

Combined subthalamic and nucleus basalis of Meynert deep brain stimulation for Parkinson’s disease with dementia (DEMPARK-DBS): protocol of a randomized, sham-controlled trial

Abstract Introduction Dementia in Parkinson’s disease (PDD) is a common non-motor symptom of advanced disease, associated with pronounced neocortical cholinergic deficits due to neurodegeneration of the nucleus basalis of Meynert (NBM) and its cholinergic terminals. In advanced PD, patients often re...

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Bibliographic Details
Main Authors: Christine Daniels, Frank Steigerwald, Philipp Capetian, Cordula Matthies, Uwe Malzahn, Peter U. Heuschmann, Jens Volkmann
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Neurological Research and Practice
Subjects:
Deep brain stimulation
Nucleus basalis of Meynert
Parkinson’s disease
Parkinson’s disease dementia
Subthalamic nucleus
Online Access:http://link.springer.com/article/10.1186/s42466-020-00086-w

Internet

http://link.springer.com/article/10.1186/s42466-020-00086-w

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