Histone H3R2 Symmetric Dimethylation and Histone H3K4 Trimethylation Are Tightly Correlated in Eukaryotic Genomes

The preferential in vitro interaction of the PHD finger of RAG2, a subunit of the V(D)J recombinase, with histone H3 tails simultaneously trimethylated at lysine 4 and symmetrically dimethylated at arginine 2 (H3R2me2sK4me3) predicted the existence of the previously unknown histone modification H3R...

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Bibliographic Details
Main Authors: Chih-Chi Yuan, Adam G.W. Matthews, Yi Jin, Chang Feng Chen, Brad A. Chapman, Toshiro K. Ohsumi, Karen C. Glass, Tatiana G. Kutateladze, Mark L. Borowsky, Kevin Struhl, Marjorie A. Oettinger
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124711000180