Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism

Abstract Iron status is known to be associated with the physiology of adipose tissue (AT). We aimed to investigate AT heme and expression of heme exporter (FLVCR1) in association with obesity and type 2 diabetes (T2D). Substantial amounts of FLVCR1 mRNA and protein levels were detected in AT, being...

Full description

Bibliographic Details
Main Authors: José María Moreno-Navarrete, Amaia Rodríguez, Francisco Ortega, Sara Becerril, Mònica Sabater-Masdeu, Jessica Latorre, Wifredo Ricart, Gema Frühbeck, José Manuel Fernández-Real
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05597-2