Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions

The transportation of large molecules through the vascular endothelium presents a major challenge forin vivodrug delivery. Here, the authors demonstrate the potential of using external magnetic fields and magnetic nanoparticles to enhance the local extravasation of circulating large molecules.

Bibliographic Details
Main Authors: Yongzhi Qiu, Sheng Tong, Linlin Zhang, Yumiko Sakurai, David R. Myers, Lin Hong, Wilbur A. Lam, Gang Bao
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15594