Phenotype-Based Genetic Association Studies (PGAS)—Towards Understanding the Contribution of Common Genetic Variants to Schizophrenia Subphenotypes

Phenotype-Based Genetic Association Studies (PGAS)—Towards Understanding the Contribution of Common Genetic Variants to Schizophrenia Subphenotypes

Neuropsychiatric diseases ranging from schizophrenia to affective disorders and autism are heritable, highly complex and heterogeneous conditions, diagnosed purely clinically, with no supporting biomarkers or neuroimaging criteria. Relying on these “umbrella diagnoses”, genetic analyses, including g...

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Bibliographic Details
Main Authors: Hannelore Ehrenreich, Klaus-Armin Nave
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Genes
Subjects:
mental disease
diagnosis
classification systems
GWAS
monozygotic twins
deep phenotyping
Manhattan plot
genotype
SNP
GRAS data collection
Online Access:http://www.mdpi.com/2073-4425/5/1/97

Internet

http://www.mdpi.com/2073-4425/5/1/97

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