In vivo binding and retention of CD4-specific DARPin 57.2 in macaques.

In vivo binding and retention of CD4-specific DARPin 57.2 in macaques.

The recently described Designed Ankyrin Repeat Protein (DARPin) technology can produce highly selective ligands to a variety of biological targets at a low production cost.To investigate the in vivo use of DARPins for future application to novel anti-HIV strategies, we identified potent CD4-specific...

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Bibliographic Details
Main Authors: Pavel Pugach, Anders Krarup, Agegnehu Gettie, Marcelo Kuroda, James Blanchard, Michael Piatak, Jeffrey D Lifson, Alexandra Trkola, Melissa Robbiani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2929209?pdf=render

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http://europepmc.org/articles/PMC2929209?pdf=render

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