Haplotype association analysis of combining unrelated case-control and triads with consideration of population stratification

Combining data when data are collected under different study designs, such as family trios and unrelated case-control samples, gains more power and is cost-effective than analyzing each data separately. However, a potential concern is population stratification (PS) among unrelated case-control sampl...

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Bibliographic Details
Main Authors: Shu-Hui eWen, Miao-Yu eTsai
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00103/full