Combined Effects of Benidipine and Diltiazem in a Rat Model of Experimental Angina

We examined the combined effects of the calcium channel blockers 1,4-dihydropyridine (benidipine) and benzothiazepine (diltiazem) on vasopressin-induced myocardial ischemia in anesthetized rats, an experimental model of angina. Benidipine (3, 10 μg/kg, i.v.) and diltiazem (300, 1000 μg/kg, i.v.) cau...

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Bibliographic Details
Main Authors: Kozo Yao, Shiro Shirakura
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319324211