Single-cell transcriptome and TCR profiling reveal activated and expanded T cell populations in Parkinson’s disease
Abstract Given the chronic inflammatory nature of Parkinson’s disease (PD), T cell immunity may be important for disease onset. Here, we performed single-cell transcriptome and TCR sequencing, and conducted integrative analyses to decode composition, function and lineage relationship of T cells in t...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Cell Discovery |
Online Access: | https://doi.org/10.1038/s41421-021-00280-3 |