Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice

<p>Abstract</p> <p>Background</p> <p>Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) with unknown etiology. Interferon-β (IFN-β), a member of the type I IFN family, is used as a therapeutic for MS and the IFN signaling pathway is i...

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Bibliographic Details
Main Authors: Salem Mohammad, Mony Jyothi T, Løbner Morten, Khorooshi Reza, Owens Trevor
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Neuroinflammation
Subjects:
EAE
Online Access:http://www.jneuroinflammation.com/content/8/1/181