KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in the context of p53 loss through miR-192 targeting of ZEB2

Krüppel-like factor 5 (KLF5) can both promote and suppress cell migration, but the underlying mechanisms have not been elucidated. In this study, we show that the function of KLF5 in epithelial-mesenchymal transition (EMT) and migration of liver cancer cells depends on the status of the cellular tum...

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Bibliographic Details
Main Authors: Lan Sun, Xiaona Zhou, Yanmeng Li, Wei Chen, Shanna Wu, Bei Zhang, Jingyi Yao, Anjian Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Cell Adhesion & Migration
Subjects:
Online Access:http://dx.doi.org/10.1080/19336918.2020.1826216