In Vivo Performance and Properties of Tamoxifen Metabolites for CreERT2 Control.

In Vivo Performance and Properties of Tamoxifen Metabolites for CreERT2 Control.

Mutant Estrogen Receptor (ERT2) ligand-binding domain fusions with Cre recombinase are a key tool for spatio-temporally controlled genetic recombination with the Cre/lox system. CreERT2 is efficiently activated in a concentration-dependent manner by the Tamoxifen metabolite trans-4-OH-Tamoxifen (tra...

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Bibliographic Details
Main Authors: Anastasia Felker, Susan Nieuwenhuize, Aymeric Dolbois, Kristyna Blazkova, Christopher Hess, Larry W L Low, Sibylle Burger, Natasha Samson, Tom J Carney, Petr Bartunek, Cristina Nevado, Christian Mosimann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4831813?pdf=render

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http://europepmc.org/articles/PMC4831813?pdf=render

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