Clinical significance of ERBB2 exon 16 skipping: analysis of a real-world retrospective observational cohort study
Background ERBB2 exon 16 skipping is an alternatively spliced isoform of ERBB2, which was reported to lead to oncogenic activation of ERBB2 and could potentially cause tyrosine kinase inhibitor (TKI) resistance in non-small cell lung cancer (NSCLC) in case studies. In this study, we aimed to evaluat...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-12-01
|
| Series: | ESMO Open |
| Online Access: | https://esmoopen.bmj.com/content/5/6/e000985.full |