Schistosoma japonicum soluble egg antigens attenuate invasion in a first trimester human placental trophoblast model.

Schistosomiasis affects nearly 40 million women of reproductive age, and is known to elicit a pro-inflammatory signature in the placenta. We have previously shown that antigens from schistosome eggs can elicit pro-inflammatory cytokine production from trophoblast cells specifically; however, the inf...

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Bibliographic Details
Main Authors: Emily A McDonald, Jennifer F Friedman, Surendra Sharma, Luz Acosta, Sunthorn Pond-Tor, Ling Cheng, Eric S White, Jonathan D Kurtis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3675010?pdf=render