The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90

The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90

The aryl hydrocarbon receptor is a member of the nuclear receptor superfamily that associates with the molecular chaperone HSP90 in the cytoplasm. The activation mechanism of the AhR is not yet fully understood. It has been proposed that after binding of ligands such as 2,3,7,8-tetrachlorodibenzo-p-...

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Bibliographic Details
Main Authors: Noriko Tsuji, Kana Fukuda, Yuhtaroh Nagata, Hirotaka Okada, Asami Haga, Shiori Hatakeyama, Shiho Yoshida, Tomoya Okamoto, Miki Hosaka, Kazuhiro Sekine, Kei Ohtaka, Soh Yamamoto, Michiro Otaka, Ewa Grave, Hideaki Itoh
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
Aryl hydrocarbon receptor
AhR
Dioxin receptor
Molecular chaperone
HSP90
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546314000850

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http://www.sciencedirect.com/science/article/pii/S2211546314000850

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