Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation.

Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector protein via the cag-Type IV Secretion System (cag-T4SS) into host cells is a hallmark of infection with Hp and a major risk factor for severe gastric diseases, including gastric cancer. To mediate the injection...

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Bibliographic Details
Main Authors: Qing Zhao, Benjamin Busch, Luisa Fernanda Jiménez-Soto, Hellen Ishikawa-Ankerhold, Steffen Massberg, Laurent Terradot, Wolfgang Fischer, Rainer Haas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6231679?pdf=render