Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation.
Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector protein via the cag-Type IV Secretion System (cag-T4SS) into host cells is a hallmark of infection with Hp and a major risk factor for severe gastric diseases, including gastric cancer. To mediate the injection...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-10-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC6231679?pdf=render |