Evaluation of Meropenem Pharmacokinetics in an Experimental Acute Respiratory Distress Syndrome (ARDS) Model during Extracorporeal Membrane Oxygenation (ECMO) by Using a PenP β-Lactamase Biosensor

Evaluation of Meropenem Pharmacokinetics in an Experimental Acute Respiratory Distress Syndrome (ARDS) Model during Extracorporeal Membrane Oxygenation (ECMO) by Using a PenP β-Lactamase Biosensor

Introduction: The use of antibiotics is mandatory in patients during extracorporeal membrane oxygenation (ECMO) support. Clinical studies have shown high variability in the antibiotic concentrations, as well as sequestration of them by the ECMO circuit, suggesting that the doses and/or interval admi...

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Bibliographic Details
Main Authors: Max Andresen, Joaquin Araos, Kwok-Yin Wong, Yun-Chung Leung, Lok-Yan So, Wai-Ting Wong, Salvador Cabrera, Camila Silva, Leyla Alegria, Alejandro Bruhn, Dagoberto Soto
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Sensors
Subjects:
biosensor
PenP
pharmacokinetic
meropenem
ECMO
Online Access:http://www.mdpi.com/1424-8220/18/5/1424

Internet

http://www.mdpi.com/1424-8220/18/5/1424

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