SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium.

SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium.

Expression of the cellular adhesion protein N-cadherin is a critical event during epithelial-mesenchymal transition (EMT). The SMAD4 protein has been identified as a mediator of transforming growth factor-β (TGF-β) superfamily signaling, which regulates EMT, but the mechanisms linking TGF-β signalin...

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Bibliographic Details
Main Authors: Ya'an Kang, Jianhua Ling, Rei Suzuki, David Roife, Xavier Chopin-Laly, Mark J Truty, Deyali Chatterjee, Huamin Wang, Ryan M Thomas, Matthew H Katz, Paul J Chiao, Jason B Fleming
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4180072?pdf=render

Internet

http://europepmc.org/articles/PMC4180072?pdf=render

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