Detecting Resistance to Therapeutic ALK Inhibitors in Tumor Tissue and Liquid Biopsy Markers: An Update to a Clinical Routine Practice

The survival of most patients with advanced stage non-small cell lung cancer is prolonged by several months when they are treated with first- and next-generation inhibitors targeting <i>ALK </i>rearrangements, but resistance inevitably emerges. Some of the mechanisms of resistance are se...

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Bibliographic Details
Main Author: Paul Hofman
Format: Article
Published: MDPI AG 2021-01-01
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